Acquired platelet dysfunction with eosinophilia (APDE): an underrecognised condition.
نویسندگان
چکیده
She was the youngest in a family of seven. Her siblings were well. There was no family history of bleeding disorders. On examination, she had multiple ecchymotic lesions of varying size and shape on her left forearm, gluteal regions, left leg and dorsum of both wrists. The rest of the physical examination was normal: in particular, she had no lymphadenopathy, hepatosplenomegaly or retinal haemorrhage.
منابع مشابه
Acquired Platelet Dysfunction with Eosinophilia: A Report of 3 Cases with Review of Literature
Patients who were in good health, with no history of any drug ingestion or recent travel, presented with spontaneous widespread bruising and ecchymosismainly on the extremities. No history of severe bleeding was noted. These patients on laboratory evaluation did not show any abnormalities in basic hemostatic screen with BT (Bleeding Time), CT (Clotting time), PT (Prothrombin Time), APTT (Activa...
متن کاملAcquired Platelet Dysfunction as a Cause of Bleeding Diathesis: Two Case Studies
Submit Manuscript | http://medcraveonline.com Abbreviations: APDE: Acquired Platelet Dysfunction with Eosinophilia; AEC: Absolute Eosinophil Count; ADP: Adenosine Diphosphate; RiCof: Platelet Ristocetin Cofactor; APTT: Activated Partial Thromboplastin Time; PT: Prothrombin Time; SFLC: Serum Free Light Chains; IgA: Immunoglobulin A; aVWD: Acquired Von Willebrand Disease; FVIII: Factor VIII; FIX:...
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Dear Editor, An acquired, transient bleeding disorder characterised by a thrombocytopathic bleeding with a platelet storage pool disorder has been reported from the Southeast Asian region and elsewhere since the 1960s.1,2 The condition has been coined acquired platelet dysfunction with eosinophilia (APDE) as cases reported earlier were also found to have eosinophilia. However, a large series of...
متن کاملA study of 31 patients with easy bruising from University Hospital, Kuala Lumpur.
Thirty one patients were investigated for the main complaint of easy bruising. These patients had normal platelet count with no past history of immune thrombocytopenia or systemic disorders known to predispose to bruising and a negative drug history. The evaluation of these patients included clinical review (history and physical examination) plus coagulation tests consisting of bleeding time, p...
متن کاملUnusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia
An 11-year-old American boy was staying with his family in Indonesia. He presented with a 5-month history of recurrent bruises and ecchymosis. A clinical diagnosis of acquired platelet dysfunction with eosinophilia was made when his full blood counts showed hypereosinophilia (7.4×10(9)/L) with normal platelet count and gray platelets under the microscope. The diagnosis was supported by abnormal...
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عنوان ژورنال:
- The Medical journal of Malaysia
دوره 42 1 شماره
صفحات -
تاریخ انتشار 1987